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PureGenomics® B-Complex 120's

Broad-spectrum B vitamin support for common genetic variations

Retail Price

Benefits & Features

  • Addresses the nutrient requirements of common genetic variations in the methylation pathway
  • Supports cellular health, DNA synthesis, hormone and neurotransmitter production, and energy metabolism
  • Promotes energy production and nutrient metabolism
  • Offers vitamin B12 in unique blend of adenosylcobalamin and hydroxycobalamin
  • Contains Metafolin® L-5-MTHF, the naturally occurring, universally metabolized form of folate
  • Part of the PureGenomics® product line
  • Made with high-quality vegan ingredients backed by verifiable science


  • Ages 18 and up
  • Support for common genetic variations
  • B vitamin and general wellness support

Suggested Use

As a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional.

Science & Research

Verifiable Science

PureGenomics® B-Complex is designed to address the nutrient requirements of common genetic variations in the methylation pathway with a unique blend of B vitamins in highly researched and activated forms. Methylation is a key regulator of genetic expression and cellular function. Healthy methylation is vital for cellular health, DNA synthesis, hormone and neurotransmitter production and energy metabolism.1 Optimal levels of B vitamins have been associated with cellular, cardiovascular, neurological and psychological health.2,3,4,5 B vitamins are essential to basal mitochondrial function as metabolic coenzymes, playing a key role in energy production and nutrient metabolism.6 Folate is offered in this formula as Metafolin® 5-methyltetrahydrofolate (5-MTHF), the universally metabolized and biologically active form of folate, providing support for individuals with genetic variations in the MTHFR gene.7 Vitamin B12 is offered as a combination of hydroxycobalamin and adenosylcobalamin. Hydroxycobalamin is a precursor form of vitamin B12 converted in the body to both methylcobalamin and adenosylcobalamin. Adenosylcobalamin is an activated form stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism and healthy synthesis of neuronal myelin.8 Benfotiamine is a lipid-soluble, enhanced-retention thiamin derivative.


  1. Glier MB, Green TJ, Devlin AM. Mol Nutr Food Res 2014 Jan;58(1):172-82.
  2. Antoniades C, et al. Circulation. 2006 Sep 12;114(11):1193-201.
  3. den Heijer M, et al. Arterioscler Thromb Vasc Biol. . 1998 Mar;18(3):356-61
  4. Jacobs AM, et al. Rev Neurol Dis. 2011;8(1-2):39-47.
  5. Almeida OP, et al. Ann Neurol. 2010 Oct;68(4):503-10.
  6. Huskisson E, Maggini S, Ruf M. J Int Med Res. 2007 May-Jun;35(3):277-89.
  7. Prinz-Langenohl R, et al.Br J Pharmacol. . 2009 Dec; 158(8): 2014?2021.
  8. L?vblad K, et al. Pediatr Radiol. 1997 Feb;27(2):155-8.


Gluten Free GMO Free Vegan Vegetarian

Additional Information


If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.


Store in a cool, dry place.


  • Vitamin B1 (thiamin HCl and benfotiamine), niacinamide, niacin, vitamin B5 (calcium pantothenate), vitamin B6 (pyridoxal HCl), folic acid (Metafolin® L-5-MTHF), biotin and choline are synthetic
  • Vitamin B2 (riboflavin) and vitamin B12 (hydroxycobalamin and adenosylcobalamin) are derived from corn dextrose fermentation
  • Ascorbyl palmitate is produced from corn dextrose fermentation and palm oil