Furness D and Taylor P. Australasian College of Nutritional & Environmental Medicine Journal. 2025 Sep.
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Research Publications
We know research is essential. That’s why we are committed to leading, supporting, and funding clinical research initiatives, which have helped us build a robust and growing body of published research that helps further the science behind our nutritional supplements.
Our commitment to high-quality research has fueled significant discoveries in nutrition science and each year results in new peer-reviewed publications in top scientific journals.
Investigator-Initiated Research Application
We are proud to support investigator-initiated research for nearly 20 years. While we aim to support as many studies as possible, regretfully, we cannot accommodate all applicants. In order for us to properly evaluate your request, please complete this application.
Published Research
2024 - Present
Effects of Probiotic Use on Gastrointestinal Symptoms in the Late Postoperative Period of Bariatric Surgery: A Cross-Over, Randomized, Triple-Blind, Placebo-Controlled Study
Wagner NRF, Lopes MCP, Fernandes R, et al. Obes Surg. 2024 Apr;34(4):1306-1315.. 2025 Sep.
A Series of Personalized Melatonin Supplement Interventions for Poor Sleep: Feasibility Randomized Crossover Trial for Personalized N-of-1 Treatment
Butler MJ, Chandereng T, Ahn H, et al. JMIR Form Res. 2025 Sep 26;9:e58192.
Low-Dose Oral Ginger Improves Daily Symptom Scores in Asthma
Emala CW, Saroya TK, Miao Y, et al. Pharmaceuticals (Basel). 2024 Dec 8;17(12):1651.
Influence of folic acid and vitamin B12 supplementation on arsenic methylation: A double-blinded, placebo-controlled trial in Bangladeshi children
Martinez-Morata I, Parvez F, Wu H, et al Environ Int. 2024 May;187:108715.
2021 - 2023
A nutrition and lifestyle-focused shared medical appointment in a resource-challenged community setting: a mixed-methods study
Bharmal N, Beidelschies M, Alejandro-Rodriguez M, et al. BMC Public Health. 2022 Mar 7;22(1):447.
A toxicological evaluation of lithium orotate
Murbach TS, Glávits R, Endres JR, et al. Regul Toxicol Pharmacol. 2021 Aug;124:104973.
Correlative Analysis of Vitamin D and Omega-3 Fatty Acid Intake in Men on Active Surveillance for Prostate Cancer
Campbell RA, Li J, Malone L, Levy DA. Urology. 2021 Sep;155:110-116.
2018- 2020
Polyphenols From Grape and Blueberry Improve Episodic Memory in Healthy Elderly with Lower Level of Memory Performance: A Bicentric Double-Blind, Randomized, Placebo-Controlled Clinical Study
Bensalem J, Dudonné S, Etchamendy N, et al. J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):996-1007.
Ginger and its bioactive component 6-shogaol mitigate lung inflammation in a murine asthma model
Yocum GT, Hwang JJ, Mikami M, et al. Am J Physiol Lung Cell Mol Physiol. 2020 Feb 1;318(2):L296-L303.
Randomized Trial of Magnesium Glycinate Supplementation and Blood Pressure in Middle-aged Adults
Sesso H, Copeland T, Coates J, et al. Hypertension.
2020;76(suppl 1).
Orally Administered Alpha Lipoic Acid as a Treatment for Geographic Atrophy: A Randomized Clinical Trial
Kim B, Hunter A, Brucker A, et al. Ophthalmol Retina. 2020 Sep;4(9):889-898.
Comparing the Gastrointestinal Tolerability & Absorption of Racemic Lipoic Acid & R-lipoic acid in Progressive Multiple Sclerosis: A Cross-Over Trial
Cameron M, Taylor C, Lapidus J, et al. J Clin Pharmacol. 2020
Mar 25.
Polyphenols from Grape & Blueberry Improve Episodic Memory in Healthy Elderly with Lower Level of Memory Performance: A Bicentric Double-Blind, Randomized, Placebo-Controlled Clinical Study
Bensalem J, Dudonné S, Etchamendy N, et al. J Gerontol A Biol
Sci Med Sci. 2019 Jun 18;74(7):996-1007.
Effect of Vitamin D Supplementation on 25(OH)D Status in Elite Athletes With Spinal Cord Injury
Pritchett K, Pritchett RC, Stark L, et al. Int J Sport Nutr
Exerc Metab. 2018 Sep 8:1-6.
Weekly vitamin D supplementation increased vitamin D
concentrations in elite athletes with spinal cord injury and improved handgrip
strength in 62% of participants, post supplementation.
Research Publications
08/09/2018
2015-2017
Strawberry and cranberry polyphenols improve insulin sensitivity in insulin-resistant, non-diabetic adults: a parallel, double-blind, controlled and randomised clinical trial
Paquette M, Medina Larqué AS, Weisnagel SJ, et al. Br J Nutr. 2017 Feb;117(4):519-531.
A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study
Allaire J, Couture P, Leclerc M, et al. Am J Clin Nutr. 2016 Aug;104(2):280-7.
Potentiation of the bioavailability of blueberry phenolic compounds by co-ingested grape phenolic compounds in mice, revealed by targeted metabolomic profiling in plasma and feces
Dudonné S, Dal-Pan A, Dubé P, et al. Food Funct. 2016 Aug 10;7(8):3421-30.
Gut microbiota composition in relation to the metabolic response to 12-week combined polyphenol supplementation in overweight men & women
Most J, Penders J, Lucchesi M, et al. Eur J Clin Nutr. 2017
Sep;71(9):1040-1045.
Epigallocatechin-3-gallate and resveratrol
supplementation significantly decreased Bacteroidetes in men but not in
women.
Research Publications
17/09/2017
Lipoic Acid Pharmacokinetics at Baseline & 1 year in Secondary Progressive MS
Bittner F, Murchison C, Koop D, et al. Neurol Neuroimmunol
Neuroinflamm. 2017 Sep; 4(5): e380.
Peak serum levels of alpha lipoic acid did not
significantly change after one year of alpha lipoic acid (1,200 mg/daily)
administration, in secondary progressive MS patients.
Research Publications
04/09/2017
Lipoic acid in secondary progressive MS: A randomized controlled pilot trial
Spain R, Powers K, Murchison C, et al. Neurol Neuroimmunol
Neuroinflamm. 2017 Jun 28;4(5):e374.
The annualized percent change in brain volume was
significantly less in secondary progressive MS patients administered alpha
lipoic acid, compared to placebo.
Research Publications
28/06/2017
Strawberry & cranberry polyphenols improve insulin sensitivity in insulin-resistant, non-diabetic adults: a parallel, double-blind, controlled & randomised clinical trial
Paquette M, Medina-Larqué A, Weisnagel SJ, et al. 2017 Feb;
117(4):519-531.
Polyphenols
from strawberries and cranberries improved insulin sensitivity in overweight and
obese, non-diabetic, insulin-resistant human subjects.
Research Publications
01/02/2017
Melatonin micronutrients Osteopenia Treatment Study (MOTS): a translational study assessing melatonin, strontium (citrate), vitamin D3 & vitamin K2 (MK7) on bone density, bone marker turnover & health-related quality of life in postmenopausal osteopenic women following a one year double-blind RCT & on osteoblast osteoclast co-cultures
Maria S, Swanson M, Enderby L, et al. AGING. 2017.
In postmenopausal osteopenic women,
supplementation with melatonin, strontium, vitamin D3 and vitamin K2 increased
bone mineral density, reduced bone turnover and improved sleep quality, compared
to placebo, over the course of a year.
Research Publications
01/01/2017
Supplementation with high-dose docosahexaenoic acid increases the Omega-3 Index more than high-dose eicosapentaenoic acid
Allaire J, Harris W, Vors C, et al. PLEFA. 2017.
The increase in omega-3 index was greater with
supplemental DHA than EPA. The omega-3 index has been inversely associated with
the risk of coronary heart disease and coronary mortality.
Research Publications
01/01/2017
Inflammatory gene expression in whole blood cells after EPA vs. DHA supplementation: Results from the ComparED study
Vors C, Allaire J, Marin J, et al. Atherosclerosis.
2017.
Both EPA and DHA
up-regulated anti-inflammatory gene expression in immune cells of men and women
at risk of cardiometabolic disease.
Research Publications
01/01/2017
Effects of systemic enzyme therapy in healthy active adults after exhaustive eccentric exercise: a randomized, two-stage, double-blinded, placebo-controlled trial
Marzin T, Lorkowski G, Reule C, et al. 2017.
Wobenzym® plus supplementation before and
after exercise increased maximum concentric strength in medium performance
athletes and improved inflammatory, metabolic and immune biomarkers in all
subjects.
Research Publications
01/01/2017
Saw Palmetto for Symptom Management During Radiation Therapy for Prostate Cancer
Wyatt GK, Sikorskii A, Safikhani A, et al. J Pain Symptom
Manage. 2016 Jun;51(6):1046-1054.
Saw palmetto at a dose of 960 mg, over the course of
22 weeks, may be a safe herbal supplement in men undergoing radiation therapy
for prostate cancer.
Research Publications
01/06/2016
Efficacy, tolerability, & safety of an oral enzyme combination vs. diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials
Ueberall M, Mueller-Schwefe G, Wigand R and Essner U. J Pain
Res. 2016.
Wobenzym®
plus demonstrated comparable efficacy and superior tolerability compared to
diclofenac, in the treatment of osteoarthritis of the knee.
Research Publications
01/01/2016
Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial
Peters BA, Hall MN, Liu X, et al. J Nutr. 2016.
Creatine + folic acid supplementation decreased
plasma guanidinoacetate and total homocystiene levels.
Research Publications
01/01/2016
Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 weeks increases mitochondrial capacity & fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial
Most J, Timmers S, Warnke I, et al. Am J Clin Nutr.
2016.
EGCG+RES supplementation
did not affect the fasting plasma metabolic profile. Although whole-body fat mass
was not affected, visceral adipose tissue mass tended to decrease after the
intervention compared with placebo.
Research Publications
01/01/2016
Randomized, crossover, head-to-head comparison of EPA & DHA supplementation to reduce inflammation markers in men & women: the Comparing EPA to DHA Study
Allaire J, Couture P, Leclerc M, et al. Am J Clin Nutr.
2016.
DHA is more effective
than EPA in modulating specific markers of inflammation as well as blood
lipids.
Research Publications
01/01/2016
Dietary polyphenol supplementation prevents alterations of spatial navigation in middle-aged mice
Bensalem J, Servant L, Alfos S, et al. Front Behav Neurosci.
2016.
Polyphenol
supplementation (Neurophenol) promoted spatial strategies in middle-aged mice,
thus suggesting a role in maintaining cognitive health in aging.
Research Publications
01/01/2016
Folic Acid & Creatine as Therapeutic Approaches to Lower Blood Arsenic: A Randomized Controlled Trial
Peters BA, Hall MN, Liu X, et al. Envir Health Perspect. 2015
Dec;123(12):1294-1301.
In a
folate-deficient/replete Bangladeshi population, 12- and 24-week treatment with
800 μg (but not 400 μg) FA lowered blood arsenic levels to a greater extent than
placebo with sustained effects.
Research Publications
02/12/2015
Impact of systemic enzyme supplementation on low-grade inflammation in humans
Paradis M-E, Couture P, Gigleux I, et al. Pharma Nutr.
2015.
Systemic enzymes promoted
healthy inflammatory balance in men and women with subclinical inflammation.
Overall, subjects showed reduced IL-6 levels, with sex-specific effects that
require further study.
Research Publications
01/01/2015
Proteolytic enzyme combination reduces inflammation and oxidative stress & improves insulin sensitivity in a model of metabolic syndrome
Talaieva T, Bratus V. Adv Enzyme Res. 2015.
In a rabbit model of diet-induced MetS, animals
supplemented with systemic enzymes showed improvement in insulin sensitivity,
inflammatory markers, triglyceride metabolism, and lipid metabolism.
Research Publications
01/01/2015
The safety & efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial
Bolten W, Glade M, Raum S, et al. Arthritis. 2015.
Systemic enzymes in adults with
moderate-to-severe knee osteoarthritis showed improvement in pain scores
(Lequesne Functional Index) and total WOMAC scores similar to NSAID
(diclofenac).
Research Publications
01/01/2015
A randomized trial of nutrient supplements to minimize psychiatric illness after a natural disaster
Kaplan B, Rucklidge J, Romijn A, et al. Psych Res. 2015.
Replication of New Zealand trial
investigating the consumption of micronutrients following a disaster and the
potential benefits for mental health and mood support.
Research Publications
01/01/2015
Effect of selenium supplementation on CD4R T-cell recovery, viral suppression and morbidity of HIV-infected patients in Rwanda: a randomized controlled trial
Kamwesiga J, Mutabazi V, Kayumba J, et al. AIDS. 2015.
This randomized clinical trial
demonstrated that 24-month selenium supplementation significantly reduces the
rate of CD-4 cell count decline among antiretroviral-naive patients.
Research Publications
01/01/2015
Effect of the probiotic Saccharomyces boulardii on cholesterol & lipoprotein particles in hypercholesterolemic adults: A single-arm, open-label pilot study
Ryan J, Hanes D, Schafer M, et al. J Altern Comp Med.
2015.
In this pilot study, 8
weeks of daily supplementation with S. boulardii showed potential benefit for
cardiovascular health.
Research Publications
01/01/2015
Double-blind randomized placebo-controlled clinical trial of omega 3 fatty acids for the treatment of diabetic patients with nonalcoholic steatohepatitis
Dasarathy S, Dasarathy J, Khiyami A, et al. J Clin
Gastroenterol. 2015.
PUFA
showed no benefit over placebo in NASH patients with diabetes in terms of liver
enzymes, body weight, or body composition, and did not show a positive impact on
insulin response.
Research Publications
01/01/2015
Effect of Vitamin D3 supplementation in black & in white children: a randomized, placebo-controlled trial
Rajakumar K, Moore CG, Yabes J, et al. J Clin Endocrinol
Metab. 2015.
Concluded current
recommended daily dietary allowance of Vitamin D may not be adequate for
reducing the incidence of vitamin D insufficiency in healthy school-aged
children.
Research Publications
01/01/2015
Effect of DHA-rich fish oil on PPARγ target genes related to lipid metabolism in type 2 diabetes: A randomized, double-blind, placebo-controlled clinical trial
Mansoori A, Sotoudeh G, Djalali M, et al. J Clin Lipidol.
2015.
8 weeks of
supplementation with DHA-rich fish oil (containing 1450 mg DHA and 400 mg EPA)
supported triglyceride metabolism.
Research Publications
01/01/2015
2012-2014
Short-term supplementation with a specific combination of dietary polyphenols increases energy expenditure & alters substrate metabolism in overweight subjects
Most J, Goossens G, Jocken J, et al. Int J Obes. 2014.
Epigallocatechin-gallate plus resveratrol
supplementation for 3 days significantly increased fasting and postprandial
energy expenditure in healthy overweight subjects.
Research Publications
01/01/2014
Modulation of strawberry/cranberry phenolic compounds glucuronidation by co-supplementation with onion: characterization of phenolic metabolites in rat plasma using an optimized μSPE−UHPLC-MS/MS method
Dudonné S, Dubé P, Pilon G, et al. J Ag Food Chem.
2014.
Phenolic metabolites of
fruit polyphenols were identified and quantified in vivo using an animal model
of obesity. Results indicated a potential synergistic effect on bioavailability
when polyphenols were administered with onion extract, a significant source of
quercetin.
Research Publications
01/01/2014
Brief report: An open-label study of the neurosteroid pregnenolone in adults with an autism spectrum disorder
L Fung, R Libove, J Phillips, F Haddad, A Hardan. J Autism
Dev Disord. 2014.
12 week,
open-label pilot study in adults with autism spectrum disorder yielded
statistically significant improvement in aberrant behavior (irritability) with
pregnenolone supplementation.
Research Publications
01/01/2014
Effect of high dose fish oil supplementation on cerebral blood flow & cognitive performance in patients with mild cognitive impairment: a proof of concept study
van de Rest O, Claassen J, Kessels R, et al. J Aging Res Clin
Practice. 2013.
In this
randomized controlled trial in patients with mild cognitive impairment, daily
supplementation with EPA+DHA for four weeks had no effect on cerebral
hemodynamics, blood pressure, or cognitive performance.
Research Publications
01/01/2013
Oral high-dose multivitamins & minerals after myocardial infarction
Lamas G, Boineau R, Goertz C, et al. Annals Int Med.
2013.
High-dose oral
multivitamins and multi-minerals did not statistically significantly reduce
cardiovascular events in patients after myocardial infarction who received
standard medications, however, this conclusion may have been tempered by
nonadherence. No evidence suggested harm from vitamin therapy in any category of
adverse events.
Research Publications
01/01/2013
A placebo-controlled trial of acetyl-l-carnitine & α-lipoic acid in the treatment of bipolar depression.
Brennan BP, Jensen JE, Hudson JI, Coit CE, Beaulieu A, Pope
HG, Renshaw PF, Cohen BM. J Clin Psychopharmacol. 2013.
Alpha-lipoic acid plus acetyl-l-carnitine (Pure
Encapsulations) administered at daily doses of 1000-3000 mg and 600-1800 mg,
respectively, does not reduce bipolar depression according to a 12 week
randomized, placebo-controlled study of 40 adults. More study is needed to
understand the role of mitochondrial function in depression.
Research Publications
01/01/2013
High potency fish oil supplement improves omega-3 fatty acid status in healthy adults: an open-label study using a web-based, virtual platform.
Udani JK, Ritz BW. Nutr J. 2013;12:112.
Switching to a high potency fish oil supplement
(Minami Nutrition) at a dose of 1.1g/d (756mg EPA, 228mg DHA) further improved
Omega-3 Index in healthy subjects.
Research Publications
01/01/2013
Do Fatty Acids Really Increase Risk of Prostate Cancer?
Duffy MacKay, ND, and Barry W. Ritz, PhD.
Evaluating the results of the recent report from the
SELECT Trial.
Research Publications
01/01/2013
Acute Effects of Polyphenols from Cranberries & Grape Seeds on Endothelial Function & Performance in Elite Athletes
Labonté K, Couillard C, Motard-Bélanger A, Paradis M-E,
Couture P, Lamarche B. Sports. 2013.
Cranberry-rich polyphenols modified acute
flow-mediated dilation, a biomarker of endothelial function and blood flow, in
highly trained elite athletes.
Research Publications
01/01/2013
Hip bone loss is attenuated with 1000 IU but not 400 IU daily vitamin D3: a 1 year double-blind RCT in postmenopausal women
Macdonald HM, Wood AD, Aucott LS, Black AJ, Fraser WD,
Mavroeidi A, Reid DM, Secombes KR, Simpson WG, Thies F.J Bone Miner Res.
2013.
Vitamin D3 (Pure
Encapsulations) in a daily dose of 1000 IU, but not 400 IU, attenuated bone
mineral density loss over 1 year in post-menopausal women.
Research Publications
01/01/2013
Effects of Polygonum Cuspidatum Containing Resveratrol on Inflammation in Male Professional Basketball Players
Zahedi HS, Jazayeri S, Ghiasvand R, Djalali M, Eshraghian MR.
Int J Prev Med. 2013.
Resveratrol (Pure Encapsulations) at a dose of 200 mg
polygonum cuspidatum standardized to 20% trans-resveratrol (40 mg
trans-resveratrol) for 6 weeks helped maintain healthy inflammatory balance in
response to intense exercise.
Research Publications
01/01/2013
Zinc Lozenges for the Common Cold
Ritz BW. Natural Med J. 2012;4(1).
Commentary on a meta-analysis of 13 clinical trials
and review of the literature suggests that zinc may be effective at promoting a
healthy immune response when taken at early onset and at a dose of 75mg per
day.
Research Publications
01/01/2012
Gastrointestinal absorption & biological activities of serine & cysteine proteases of animal & plant origin: a review on the absorption of serine & cysteine proteases
Lorkowski G. Int J Physiol Pathophysiol Pharmacol.
2012;4(1):10-27.
Scientific
review of the gastrointestinal absorption of proteolytic systemic enzymes
(Wobenzym®) following oral administration, interaction with
anti-proteases and proteolytic activity in the blood, and a plausible mechanism
for promoting healthy inflammation response.
Research Publications
01/01/2012
Anti-Inflammatory & Neuroactive Properties of Selected Fruit Extracts
Heim KC, Angers P, Léonhart S, Ritz BW. J Med Food.
2012.
Cranberry, blueberry,
strawberry, and spinach extracts exhibited dose-dependent antioxidant activity
in vitro, with implications for neurological health and anti-inflammatory
effects.
Research Publications
01/01/2012
Omega-3 Fatty Acid & Epilepsy
Ritz BW. Natural Med J. 2012.
Commentary on an open trial reporting a slight
reduction in epileptic seizure activity with eicosapentaenoic acid
supplementation.
Research Publications
01/01/2012
2009-2011
Phase II study of the effects of ginger root extracts on eicosanoids in colon mucosa in patients at normal risk for colorectal cancer
Zick SM, Tugeon DK, Vareed SK, et al. Cancer Prev Res.
October 11, 2011.
Ginger root
extract (Pure Encapsulations) may decrease eicosanoid levels in colonic mucosa
and promote colon health.
Research Publications
11/10/2011
Rationale and design of the B-PROOF study, a randomized controlled trial on the effect of supplemental intake of vitamin B12 & folic acid on fracture incidence
Van Wijngaarden et al. BMC Geriatrics. 2011; 11:80.
The first intervention study examining the
effects of vitamin B12 and folic acid supplementation on osteoporotic fracture
incidence, bone health, physical performance/activity, and nutritional status in
a general elderly population presenting with elevated homocysteine
levels.
Research Publications
01/01/2011
Active Hexose Correlated Compound (AHCC) & Immune Outcomes in Humans: A Review
Ritz BW. Natural Med J. 2011;3(1).
A review of the available data suggests that AHCC, a
fermented mushroom extract, may positively affect immune function, especially
natural killer cell-mediated innate immunity.
Research Publications
01/01/2011
Effect of selenium supplementation on CD4 T-cell recovery
Kamwesiga J, Mutabzi V, Kayumba J, et al. Trials.
2011;12:192.
Methods
publication of ongoing trial to investigate effects of selenium supplementation
(Seroyal) on immune function, general health and quality of life in sub-Saharan
Africa.
Research Publications
01/01/2011
An Antiinflammatory & Reactive Oxygen Species Suppressive Effects of an Extract of Polygonum Cuspidatum Containing Resveratrol
Ghanim H, Sia CL, Abuaysheh S, Korzeniewski K, Patnaik P,
Marumganti A, Chaudhuri A, Dandona P. J Clin Endocrinol Metab. 2010.
Resveratrol (Pure Encapsulations) at a dose of
200 mg polygonum cuspidatum standardized to 20% trans-resveratrol (40 mg
trans-resveratrol) for 6 weeks helped attenuate oxidative and inflammatory
stress in normal, healthy subjects.
Research Publications
01/01/2010
Naturopathic Treatment of Rotator Cuff Tendinitis Among Canadian Postal Workers: A Randomized Controlled Trial
Szczurko O, Cooley K, Mills EJ, et al. Arthritis &
Rheumatology (Arthritis Care & Research). 2009;61(8):1037-1045.
As part of a comprehensive naturopathic
protocol, promoted joint function and quality of life in a prospective
trial.
Research Publications
01/01/2009
2006-2008
Pharmacokinetics of 6-Gingerol, 8-Gingerol, 10-Gingerol, & 6-Shogaol & Conjugate Metabolites in Healthy Human Subjects
Zick Sm, Djuric Z, Ruffin MT, et al. Cancer Epidemiol
Biomarkers Prev. 2008;17(8).
Tolerability and pharmacokinetics of ginger (Pure
Encapsulations) constituents demonstrated detectable metabolites in blood
following a single oral dose.
Research Publications
01/01/2008
Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea & vomiting
Zick SM, Ruffin MT, Lee J, Normolle DP, Siden R, Alrawi S,
Brenner DE. Support Cancer Care, 2008.
Ginger (Pure Encapsulations) provides no additional
benefit as an adjuvant for gastrointestinal symptoms.
Research Publications
01/01/2008
Ongoing Studies
| STUDY TITLE | INTERVENTION(S) | INSTITUTION |
|---|---|---|
| Optimal Clinical Trials Platform for Progressive Multiple Sclerosis | Alpha lipoic acid | University College London |
| Lipoic Acid for the Treatment of Progressive Multiple Sclerosis | Alpha lipoic acid | Oregon Health Science University |
| Hmong Microbiome ANd Gout Obesity, Vitamin C (HMANGO-C) Study | Ascorbic acid | University of Minnesota |
| Butyric Acid Supplementation to Improve Gut Health after Cardiac Surgery in Kids (BASICS-Kids) | Butyrate | University of Nebraska Medical Center |
| Pilot Trial to Examine the Effect of Ginger on the Gut Microbiome (GINGER) | Ginger extract | University of Minnesota |
| Trial of magnesium supplementation and blood pressure reduction among adults with elevated systolic blood pressure | Magnesium | Brigham and Women's Hospital, Harvard Medicine |
| RECOVER-SLEEP: A Platform Protocol for Evaluation of Interventions for Sleep Disturbances in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) | Melatonin | Duke Clinical Research Institute |
| A Series of Remote Melatonin Supplement Interventions for Poor Sleep: Protocol for a Feasibility Pilot Study for a Series of Personalized (N-of-1) Trials | Melatonin | Feinstein Institutes for Medical Research |
| High Dose Melatonin Add-on Therapy for the Treatment of Developmental/Epileptic Encephalopathy with Spike Wave Activation In Sleep | Melatonin | Kennedy Krieger Institute |
| Physical health function and oxidative stress after antioxidant treatment in GWI: N-Acetyl Cysteine (NAC) | N-acetyl-l-cysteine | Nova Southeastern University |
| Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (NAC ME/CFS) | N-acetyl-l-cysteine | Weill Cornell Medicine |
| Prefrontal glutamatergic modulation by N-acetylcysteine and mindfulness-based cognitive therapy for mild depression in youth | N-acetyl-l-cysteine | University of Cincinnati College of Medicine |
| Randomized Controlled Pilot Trial of Pregnenolone in Autism | Pregnenolone | Stanford School of Medicine |
| Assessment of Diabetes Control, Cost of Care, and Quality of Life Utilizing a Functional Medicine Approach in Addition to Usual Care vs. Usual Care Alone | Various | Cleveland Clinic |
Independent studies are conducted by independent, academic researchers. Atrium Innovations has no influence on study results. Study titles are provided for informational purposes only and are not intended as product claims or to imply a positive outcome.