PureGenomics® Practitioner and Patient Resources
The tools below were designed to help healthcare practitioners successfully implement PureGenomics® in their practice.
FOR HEALTHCARE PRACTITIONERS
 PureGenomics® Brochure Download Order code: PGB18 |
Silent SNPs: When Genetic Test Information Matters, and When It Doesn’t
Presented by Kelly Heim, Ph.D., and Nathan Morris, M.D.+
Knowing a patient's genetic makeup can reduce trial and error, and improve the precision of nutritional protocols. However, single nucleotide polymorphisms (SNPs) often interact with environmental factors that either magnify or diminish their clinical significance. Accordingly, a SNP can be impactful in some patients, but not others. In this webinar, Kelly Heim, Ph.D., and Nathan Morris, M.D., will provide practical tips on how to identify important clues, exclude irrelevant information, and prioritize next steps on an individual basis.
Mind Over Genetic Matter: How to Address 6 Common Genetic Variations Affecting Mood and Memory‡
Presented by Kelly Heim, Ph.D., and Nathan Morris, M.D.+
Many single nucleotide polymorphisms (SNPs) have been associated with cognitive function and mental health. However, only a small number are well-researched and nutritionally responsive. In this webinar, you will learn how to test for SNPs that are clinically relevant in mental and neurocognitive contexts. You will also learn how to use this genetic information to tailor nutritional approaches in a simple, cost-effective manner.‡
The Needle in a Nutrigenetics Haystack: When Does a Genetic Test Make a Difference in a Patient’s Outcome?
Presented by Kelly Heim, Ph.D., and Nathan Morris, M.D.+
Within every patient’s genome are opportunities to optimize health and wellness. Millions of genetic variations are known, but only a small number are ready for clinical translation. In this webinar, Kelly Heim, Ph.D., and Nathan Morris, M.D., will separate fact from myth and provide tips and tricks to identify genetic opportunities for better patient management and outcomes while avoiding common, time-consuming and costly mistakes. Practitioners will take away a helpful checklist that can simplify their navigation of the rapidly evolving and highly promising field of nutritional genomics.
Is Your Weight in Your ‘Genes?’ How to Maximize the Success of a Weight Management Program by Addressing 3 Common Genetic Variations‡
Presented by Kelly Heim, Ph.D., and Nathan Morris, M.D.+
Genetic factors account for 40-90% of inter-individual differences in body weight. While many single nucleotide polymorphisms (SNPs) have been associated with fat mass, food cravings, satiety and glucose disposal, only a small number are well-researched and nutritionally responsive. In this webinar, you will learn how to test for SNPs affecting critical determinants of body weight in a simple, cost-effective manner. You will also learn how to use this genetic information to tailor nutritional guidance and simplify supplement selection to guide patients to their weight management and/or metabolic health goals.‡
Methylation and Nutrigenetics: How to Assess 8 Important Genetic Polymorphisms and Individualize Nutritional Support with the New PureGenomics® Website Application‡
Presented by Kelly Heim, Ph.D., and Nathan Morris, M.D.+
Testing for common genetic variations enables practitioners to more effectively treat patients and their individual needs. Over half of the population carries genetic variations known as single nucleotide polymorphisms (SNPs) that affect the methylation pathway. However, genetic test results are difficult to interpret and translate to effective nutritional support. In this webinar, functional medicine practitioner Nathan Morris, M.D. and pharmacologist Kelly Heim, Ph.D. will define 8 clinically important methylation SNPs that collectively affect over 50% of the population. Learn how to use PureGenomics®, a dynamic practitioner-exclusive website application that receives 23andMe® test results, identifies key methylation SNPs, and translates results into specific nutritional supplement recommendations from the PureGenomics® product platform. A live tutorial will demonstrate how easy it is to log in, manage patients, view and download reports, and select targeted supplements with precision and confidence.‡
Vitamins A and D: How to Address 3 Common Genetic Polymorphisms Affecting Serum Levels‡
Presented by Kelly C. Heim, Ph.D.
From immune function to vision, vitamins A and D are fundamental to nearly every aspect of health and wellness.‡ Common genetic variations known as Single Nucleotide Polymorphisms (SNPs) are associated with lower blood levels of these nutrients and suboptimal responses to supplementation.
Oxidative Stress and Detoxification: How to Assess 4 Important Genetic Polymorphisms to Individualize Nutritional Support with the PureGenomics® Website Application‡
Presented by Kelly C. Heim, Ph.D.
Toxins are inevitable byproducts of energy production and metabolism. Efficient clearance of these substances, which include reactive oxygen species, estrogens, homocysteine and neurotransmitter metabolites, is essential for health and wellness. Single Nucleotide Polymorphisms (SNPs) affect detoxification by compromising the activity of antioxidant and phase II enzymes. In this webinar, Kelly Heim, Ph.D. will provide practical guidance on how to distill genetic test reports to identify and address four common, well-researched Single Nucleotide Polymorphisms through targeted nutritional support.‡
+Dr. Morris has been retained as a consultant in advising Pure Encapsulations.
Select a protocol below to download.
The SNP Series Emails series includes concise, up-to-date information on genetic variations known as Single Nucleotide Polymorphisms (SNPs). Featuring one SNP at a time, the SNP series will educate you about prevalence, important research findings, targeted nutritional supplements and monitoring.‡
Click on the SNP below to view, and/or share with your colleagues through email or your social network.
1. Are dosage suggestions for the products included in the report?
The dosage does not differ from the recommendation on the product label. Other assessment methods may be used to arrive at a precise dosage. For example, measuring serum folate may provide insight into how much folate is needed. However, the recommendations on the product label will be appropriate for the majority of individuals.
2. If blood levels or other lab values do not indicate a nutrient deficiency but the PureGenomics® report recommends a supplement, how would one proceed?
A SNP cannot diagnose a nutrient deficiency. However, a SNP helps to identify whether a patient is likely to require additional amounts of a specific form of a nutrient. Nutritional assessment testing is useful in making final decisions regarding the need for supplementation.
3. Do I need to dispense all recommended supplements for a given SNP?
For several SNPs, multiple supplements are suggested. However, the patient may not require all of them. The selection can by fine-tuned by assessing nutrient levels or other types of testing you would normally include in patient evaluation. ‡
4. Do my genetic results from other genetic testing labs work with PureGenomics.com?
PureGenomics.com is only compatible with 23andMe® and AncestryDNA® genetic data.
5. Can I order 23andMe® or AncestryDNA® genetic test kits through Pure Encapsulations
You can order the kits directly through www.23andMe.com or Ancestry.com. Please note that Pure Encapsulations is not affiliated with or endorsed by 23andMe® or AncestryDNA®.
6. I have already received 23andMe® or AncestryDNA® genetic test results for myself and family. How do I process the results via the PureGenomics® platform?
Simply register at PureGenomics.com with your Pure Encapsulations account number and last name. Follow the steps on “Getting Started for Practitioners” on the homepage.
7. I have been ordering with a distributor. Do I need to set up an account with Pure Encapsulations in order to use PureGenomics.com?
Yes, you will need a Pure Encapsulations account number in order to use PureGenomics.com. Please call 866-856-9954 to speak with a Customer Service Representative or register for an account online at www.PureEncapsulations.com.
8. Can I order from 23andMe® or AncestryDNA® directly on their website or do I need to login to PureGenomics.com first?
You must order 23andMe® and AncestryDNA® genetic testing kits directly from their websites and do not need to login to PureGenomics.com to do so.
9. What is the cost to use PureGenomics.com?
PureGenomics.com is free to use!
10. How long after patients complete the genetic test will they get their raw data?
Patients will receive their test results within 6 to 8 weeks.
11. How long does it take to have the genetic data interpreted PureGenomics.com?
Once the genetic data is uploaded, the patients will see their results immediately. This information will automatically be populated to the practitioner’s dashboard.
12. Can I register my patients for PureGenomics.com if they have not received their genetic test results yet?
Yes, you can add patients and they can then register on PureGenomics.com regardless of whether or not they have received their genetic test results yet. They can upload their genetic data when they are notified by 23andMe® or AncestryDNA® that their genetic test results are ready.
SNP FAQ
1. If there are millions of SNPs, why does the report only show a limited number?
Most SNPs have no effect on physiology and therefore lack medical relevance. PureGenomics® includes SNPs that are:
- relevant to health;
- validated by published research; and
- responsive to nutritional support.
2. PureGenomics® is a dynamic and evolving website application and new SNPs meeting these criteria will be added over time. Will I need to repeat the 23andMe® or AncestryDNA® genetic test kits?
Since a person’s genome sequence cannot change, the test only needs to be performed once.
3. A patient has a -/- (green) result for FUT2, and vitamin B12 was recommended. Why?
In this case, having a SNP actually offers some degree of protection from B12 deficiency. Research suggests that this SNP increases B12 absorption, as studies link +/+ and +/- results with higher B12 levels. In a meta-analysis, serum B12 levels averaged 44 pg/ml higher in SNP carriers compared to -/- genotypes. Patients with a -/- genotype, or absence of the SNP, particularly vegetarians, are likely to benefit from supplementation. ‡
PRODUCT FAQ
1. When is adenosyl/hydroxycobalamin recommended over methylcobalamin?Individuals with the COMT Val/Met SNP commonly report feeling stimulated or restless when supplementing with methylcobalamin. This effect is seldom observed with hydroxy- and adenosylcobalamin. Both forms are effective for vitamin B12 repletion and maintaining healthy levels. ‡
"23andMe®" is the registered trademark of 23andMe®, Inc. Pure Encapsulations is not affiliated with or endorsed by 23andMe®.
AncestryDNA® is a registered trademark of Ancestry.com Operations, Inc. Pure Encapsulations is not affiliated with or endorsed by AncestryDNA®.
PureGenomics nutritional information is not intended for use in the diagnosis, cure, mitigation, treatment or prevention of disease.
‡These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
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Introduction to PureGenomics®
Navigating PureGenomics®
Creating an E-script
FOR YOUR PATIENTS
Visit PureEncapsulations.com to order copies for your office and/or share with your patients.
 PureGenomics® Patient Trifold Brochure Download Order code: PGP18 |
Introduction to PureGenomics®