Homocysteine Factors

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HO1/ HO6
Supports healthy homocysteine metabolism and cardiovascular health
Starting From $27.00



Retail Price

HO1/ HO6


Pure Encapsulations® products are formulated using high-quality, pure ingredients, FREE FROM unnecessary additives and many common allergens including:

Wheat, Soy, Dairy, Eggs
Artificial Colors & Sweeteners
Coatings & Shellacs
Tree Nuts, Peanuts & Sesame
Unnecessary Binders, Fillers & Preservatives
Magnesium Stearate
Trans Fat & Hydrogenated Oils

Benefits & Features

  • Promotes cardiovascular health
  • Supports homocysteine metabolism
  • Provides a highly bioavailable combination of vitamin B6 , vitamin B12 , folate and betaine
  • Contains Metafolin® (L-5-MTHF), the naturally occurring, universally metabolized form of folate
  • Made with high-quality vegan ingredients backed by verifiable science


  • Ages 18 and up
  • Cardiovascular health support

Suggested Use

As a dietary supplement, take 1 capsule, 2 times daily, with meals.

Science & Research

Verifiable Science

Clinical studies show that folate, vitamin B12 , and vitamin B6 are vital in the metabolism of homocysteine. Vitamin B12 and folate (L-5-MTHF) are required by the enzyme that converts homocysteine back to methionine.1 Vitamin B6 is required in each of the two enzymatic reactions that convert homocysteine to cysteine.2 Betaine, in the form of trimethylglycine, is included in this supplement to promote the methylation of homocysteine.3 Homocysteine Factors provides vitamin B6 , vitamin B12 , folate and betaine, a highly bioavailable combination of nutrients integral to maintaining healthy homocysteine metabolism and cardiovascular health.


  1. Halsted CH, et al. Proc Natl Acad Sci USA. 2002 Jul 23;99(15):10072-7.
  2. den Heijer M, et al. Arterioscler Thromb Vasc Biol. 1998 Mar;18(3):356-61.
  3. Schwab U, et al. J Nutr. 2006 Jan;136(1):34-8.

Additional Information


If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.


Store in a cool, dry place.


  • Vitamin B12 is derived from corn dextrose fermentation
  • Vitamin B6 and folic acid (Metafolin® , L-5-MTHF) are synthetically produced
  • Betaine is originally derived from sugar beet molasses and undergoes an extensive purification process
  • Vitamin C (Ascorbyl palmitate) is derived from corn dextrose fermentation and palm oil
  • Hypoallergenic plant fiber is derived from pine cellulose

Free From

Gluten Free GMO Free Vegan Vegetarian