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Folate 400 90's

Universally metabolized form of folate

Retail Price

Benefits & Features

  • Supports methylation, which maintains healthy neurotransmission, DNA synthesis and gene regulation1
  • Provides all of the benefits of folic acid regardless of MTHFR genetic variations2‡
  • Supports cardiovascular, cellular and neuronal health
  • Available in 400 mcg and 1,000 mcg
  • Offers Metafolin® L-5-MTHF, a naturally occurring, universally metabolized form of folate
  • Made with high-quality ingredients backed by verifiable science


  • Ages 18 and up
  • Universally metabolized form of folate

Suggested Use

Folate 400
As a dietary supplement, take 1 capsule, 1-2 times daily, with meals.

Folate 1,000
As a dietary supplement, take 1 capsule daily, with a meal.

Science & Research

Verifiable Science

This formula has Metafolin® L-5-methyltetrahydrofolate (L-5-MTHF), a naturally occurring, universally metabolized form of folate. Unlike folic acid, L-5-MTHF does not require activation by DHFR (dihydrofolate reductase) and MTHFR (methylene tetrahydrofolate reductase), enzymes thatare subject to functional and genetic variations that may reduce conversion efficiency.2-4‡


  1. Gropper SS, Smith JL, Groff JL. Advanced Nutrition and Human Metabolism. 5th ed. Belmont, CA: Wadsworth; 2009.
  2. Prinz-Langenohl R, et al. Br J Pharmacol. 2009 Dec; 158(8): 2014-21.
  3. Seremak-Mrozikiewicz A. Ginekol Pol.2013 Jul;84(7):641-6.
  4. Patanwala I, et al. Am J Clin Nutr. 2014 Aug;100(2):593-9.


Gluten Free GMO Free Vegan Vegetarian

Additional Information


If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.


Store in a cool, dry place.


  • Metafolin® , L-5-methyltetrahydrofolate (L-5-MTHF) is synthetic
  • Hypoallergenic plant fiber is derived from pine cellulose