Folate 1000 90's

Universally metabolized form of folate

Retail Price



Pure Encapsulations® products are formulated using high-quality, pure ingredients, FREE FROM unnecessary additives and many common allergens including:

Wheat, Soy, Dairy, Eggs
Artificial Colors & Sweeteners
Coatings & Shellacs
Tree Nuts, Peanuts & Sesame
Unnecessary Binders, Fillers & Preservatives
Magnesium Stearate
Trans Fat & Hydrogenated Oils

Benefits & Features

  • Supports methylation, which maintains healthy neurotransmission, DNA synthesis and gene regulation1
  • Provides all of the benefits of folic acid regardless of MTHFR genetic variations2‡
  • Supports cardiovascular, cellular and neuronal health
  • Available in 400 mcg and 1,000 mcg
  • Offers Metafolin® L-5-MTHF, a naturally occurring, universally metabolized form of folate
  • Made with high-quality ingredients backed by verifiable science


  • Ages 18 and up
  • Universally metabolized form of folate

Suggested Use

Folate 400
As a dietary supplement, take 1 capsule, 1-2 times daily, with meals.

Folate 1,000
As a dietary supplement, take 1 capsule daily, with a meal.

Science & Research

Verifiable Science

This formula has Metafolin® L-5-methyltetrahydrofolate (L-5-MTHF), a naturally occurring, universally metabolized form of folate. Unlike folic acid, L-5-MTHF does not require activation by DHFR (dihydrofolate reductase) and MTHFR (methylene tetrahydrofolate reductase), enzymes thatare subject to functional and genetic variations that may reduce conversion efficiency.2-4‡


  1. Gropper SS, Smith JL, Groff JL. Advanced Nutrition and Human Metabolism. 5th ed. Belmont, CA: Wadsworth; 2009.
  2. Prinz-Langenohl R, et al. Br J Pharmacol. 2009 Dec; 158(8): 2014-21.
  3. Seremak-Mrozikiewicz A. Ginekol Pol.2013 Jul;84(7):641-6.
  4. Patanwala I, et al. Am J Clin Nutr. 2014 Aug;100(2):593-9.

Additional Information


If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.


Store in a cool, dry place.


  • Metafolin® , L-5-methyltetrahydrofolate (L-5-MTHF) is synthetic
  • Hypoallergenic plant fiber is derived from pine cellulose

Free From

Gluten Free GMO Free Vegan Vegetarian